Circulating Tissue Inhibitor of Matrix Metalloproteinase-4 (TIMP-4) in Systemic Sclerosis Patients with Elevated Pulmonary Arterial Pressure

• Main Authors: Gialafos J. Elias (Author), Moyssakis Ioannis (Author), Psaltopoulou Theodora (Author), Papadopoulos P. Dimitrios (Author), Perea Despoina (Author), Vlasis Kostantinos (Author), Kostopoulos Charalampos (Author), Votteas Vassilios (Author), Sfikakis P. Petros (Author)
• Format: Book
• Published: Hindawi Limited, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Decreased levels of matrix metalloproteinases (MMPs) or excess levels of their tissue inhibitors (TIMPs) may contribute to dysregulation of extracellular matrix turnover in systemic sclerosis (SSc). In a cross-sectional study of 106 SSc patients, we measured serum levels of TIMP-4 which is preferent...