Mechanism of Dissolution Enhancement and Bioavailability of Poorly Water Soluble Celecoxib by Preparing Stable Amorphous Nanoparticles

Purpose: Nanoparticle engineering offers promising methods for the formulation of poorly water soluble drug compounds. The aim of the present work was to enhance dissolution and oral bioavailability of poorly water-soluble celecoxib (CXB) by preparing stable CXB nanoparticles using a promising metho...

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Main Authors: Yinghui Liu (Author), Changshan Sun (Author), Yanru Hao (Author), Tongying Jiang (Author), Li Zheng (Author), Siling Wang (Author)
Format: Book
Published: Frontiers Media S.A., 2010-12-01T00:00:00Z.
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