Metal-induced protein denaturation: regularities, pathological manifestations, and in vitro modeling

• Autori principali: Tetiana Popovych (Autore), Yaroslav Kizim (Autore), Natalia Obernikhina (Autore), Natalia Voroshylova (Autore)
• Natura: Libro
• Pubblicazione: Bogomolets National Medical University, 2021-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

the ability of various metal ions to form complexes with proteins leads to the denaturation of the latter and the development of immune response. Such hapten effects cause the well-known phenomenon of nickel-allergic contact dermatitis. No less typical are side effects of gadolinium compounds, that...