Characterization of acute TLR-7 agonist-induced hemorrhagic myocarditis in mice by multiparametric quantitative cardiac magnetic resonance imaging

• Main Authors: Nicoleta Baxan (Author), Angelos Papanikolaou (Author), Isabelle Salles-Crawley (Author), Amrit Lota (Author), Rasheda Chowdhury (Author), Olivier Dubois (Author), Jane Branca (Author), Muneer G. Hasham (Author), Nadia Rosenthal (Author), Sanjay K. Prasad (Author), Lan Zhao (Author), Sian E. Harding (Author), Susanne Sattler (Author)
• Format: Book
• Published: The Company of Biologists, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hemorrhagic myocarditis is a potentially fatal complication of excessive levels of systemic inflammation. It has been reported in viral infection, but is also possible in systemic autoimmunity. Epicutaneous treatment of mice with the Toll-like receptor 7 (TLR-7) agonist Resiquimod induces auto-antib...