Computational Modeling to Identify Drugs Targeting Metastatic Castration-Resistant Prostate Cancer Characterized by Heightened Glycolysis

• Главные авторы: Mei-Chi Su (Автор), Adam M. Lee (Автор), Weijie Zhang (Автор), Danielle Maeser (Автор), Robert F. Gruener (Автор), Yibin Deng (Автор), R. Stephanie Huang (Автор)
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• Опубликовано: MDPI AG, 2024-04-01T00:00:00Z.
• Предметы: article
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Metastatic castration-resistant prostate cancer (mCRPC) remains a deadly disease due to a lack of efficacious treatments. The reprogramming of cancer metabolism toward elevated glycolysis is a hallmark of mCRPC. Our goal is to identify therapeutics specifically associated with high glycolysis. Here,...