Development and validation of circulating CA125 prediction models in postmenopausal women

• Main Authors: Naoko Sasamoto (Author), Ana Babic (Author), Bernard A. Rosner (Author), Renée T. Fortner (Author), Allison F. Vitonis (Author), Hidemi Yamamoto (Author), Raina N. Fichorova (Author), Linda J. Titus (Author), Anne Tjønneland (Author), Louise Hansen (Author), Marina Kvaskoff (Author), Agnès Fournier (Author), Francesca Romana Mancini (Author), Heiner Boeing (Author), Antonia Trichopoulou (Author), Eleni Peppa (Author), Anna Karakatsani (Author), Domenico Palli (Author), Sara Grioni (Author), Amalia Mattiello (Author), Rosario Tumino (Author), Valentina Fiano (Author), N. Charlotte Onland-Moret (Author), Elisabete Weiderpass (Author), Inger T. Gram (Author), J. Ramón Quirós (Author), Leila Lujan-Barroso (Author), Maria-Jose Sánchez (Author), Sandra Colorado-Yohar (Author), Aurelio Barricarte (Author), Pilar Amiano (Author), Annika Idahl (Author), Eva Lundin (Author), Hanna Sartor (Author), Kay-Tee Khaw (Author), Timothy J. Key (Author), David Muller (Author), Elio Riboli (Author), Marc Gunter (Author), Laure Dossus (Author), Britton Trabert (Author), Nicolas Wentzensen (Author), Rudolf Kaaks (Author), Daniel W. Cramer (Author), Shelley S. Tworoger (Author), Kathryn L. Terry (Author)
• Format: Book
• Published: BMC, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer Antigen 125 (CA125) is currently the best available ovarian cancer screening biomarker. However, CA125 has been limited by low sensitivity and specificity in part due to normal variation between individuals. Personal characteristics that influence CA125 could be used to im...