Microcell-mediated chromosome transfer between non-identical human iPSCs

• Main Authors: Narumi Uno (Author), Hitomaru Miyamoto (Author), Kyotaro Yamazaki (Author), Masaya Egawa (Author), Hiroaki Kobayashi (Author), Kanako Kazuki (Author), Mitsuhiko Osaki (Author), Teruhiko Suzuki (Author), Shusei Hamamichi (Author), Mitsuo Oshimura (Author), Kazuma Tomizuka (Author), Yasuhiro Kazuki (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Microcell-mediated chromosome transfer (MMCT) is anticipated as a unique strategy to manipulate numbers of chromosomes, including the generation of hyperaneuploidy syndrome models with human induced pluripotent stem cells (hiPSCs). Mouse A9/Chinese hamster ovary (CHO) cell libraries of human monochr...