Nicorandil alleviates cardiac microvascular ferroptosis in diabetic cardiomyopathy: Role of the mitochondria-localized AMPK-Parkin-ACSL4 signaling pathway

• প্রধান লেখক: Zhangwei Chen (লেখক), Su Li (লেখক), Muyin Liu (লেখক), Ming Yin (লেখক), Jinxiang Chen (লেখক), Youran Li (লেখক), Qiyu Li (লেখক), You Zhou (লেখক), Yan Xia (লেখক), Ao Chen (লেখক), Danbo Lu (লেখক), Chenguang Li (লেখক), Yuqiong Chen (লেখক), Juying Qian (লেখক), Junbo Ge (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2024-02-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Mitochondria-associated ferroptosis exacerbates cardiac microvascular dysfunction in diabetic cardiomyopathy (DCM). Nicorandil, an ATP-sensitive K+ channel opener, protects against endothelial dysfunction, mitochondrial dysfunction, and DCM; however, its effects on ferroptosis and mitophagy remain u...