Critical appraisal of the piRNA-PIWI axis in cancer and cancer stem cells

• Κύριοι συγγραφείς: Elena Garcia-Borja (Συγγραφέας), Frantisek Siegl (Συγγραφέας), Rosana Mateu (Συγγραφέας), Ondrej Slaby (Συγγραφέας), Aleksi Sedo (Συγγραφέας), Petr Busek (Συγγραφέας), Jiri Sana (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2024-02-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Small noncoding RNAs play an important role in various disease states, including cancer. PIWI proteins, a subfamily of Argonaute proteins, and PIWI-interacting RNAs (piRNAs) were originally described as germline-specific molecules that inhibit the deleterious activity of transposable elemen...