A randomized phase II study of acyclovir for the prevention of chemotherapy-induced oral mucositis in patients undergoing autologous hematopoietic stem cell transplantation

• Main Authors: Junshik Hong (Author), Hee-Kyung Park (Author), Sung-Ho Chang (Author), Ja Min Byun (Author), Dong-Yeop Shin (Author), Youngil Koh (Author), Sung-Soo Yoon (Author), Youngnim Choi (Author), Inho Kim (Author)
• Format: Book
• Published: BMC, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objectives To prove our hypothesis that acyclovir prophylaxis in autologous hematopoietic stem cell transplantation (AHSCT) recipients with hematologic malignancies (HM) reduces the incidence of chemotherapy-induced oral mucositis (CIOM) by inhibiting the intraoral HSV reactivation during t...