Enhanced cisplatin resistance in oral-cancer stem-like cells is correlated with upregulation of excision-repair cross-complementation group 1

• Egile Nagusiak: Lo-Lin Tsai (Egilea), Cheng-Chia Yu (Egilea), Jeng-Fan Lo (Egilea), Wen-Wei Sung (Egilea), Huei Lee (Egilea), Shiow-Ling Chen (Egilea), Ming-Yung Chou (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2012-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background/purpose: Oral squamous cell carcinoma (OSCC) is a prevalent cancer worldwide. Recent data suggest that a subpopulation of cancer cells, termed cancer stem cells (CSCs), is capable of initiating, maintaining, and expanding the growth of tumors. Importantly, CSCs confer chemo- and radioresi...