Enhanced cisplatin resistance in oral-cancer stem-like cells is correlated with upregulation of excision-repair cross-complementation group 1

• Main Authors: Lo-Lin Tsai (Author), Cheng-Chia Yu (Author), Jeng-Fan Lo (Author), Wen-Wei Sung (Author), Huei Lee (Author), Shiow-Ling Chen (Author), Ming-Yung Chou (Author)
• Format: Book
• Published: Elsevier, 2012-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Oral squamous cell carcinoma (OSCC) is a prevalent cancer worldwide. Recent data suggest that a subpopulation of cancer cells, termed cancer stem cells (CSCs), is capable of initiating, maintaining, and expanding the growth of tumors. Importantly, CSCs confer chemo- and radioresi...