ERK/Nrf2 pathway activation by caffeic acid in HepG2 cells alleviates its hepatocellular damage caused by t-butylhydroperoxide-induced oxidative stress

• Main Authors: Sung-Yong Yang (Author), Min Cheol Pyo (Author), Mi-Hyun Nam (Author), Kwang-Won Lee (Author)
• 格式: 图书
• 出版: BMC, 2019-06-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract Background Several studies have found that caffeic acid (CA), a well-known phytochemical, displays important antioxidant and anti-cancer activities. However, no evidence exists on the protective effect and its mechanisms that CA treatment alone has against oxidative stress induced by tert-b...