Signal Transduction Profiling of Angiotensin II Type 1 Receptor With Mutations Associated to Atrial Fibrillation in Humans

• Main Authors: Sarah C. Simões (Author), André L. Balico-Silva (Author), Lucas T. Parreiras- (Author), André L. B. Bitencourt (Author), Michel Bouvier (Author), Claudio M. Costa-Neto (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

The AT1 receptor (AT1R) has a major role in the Renin-Angiotensin System, being involved in several physiological events including blood pressure control and electrolyte balance. The AT1R is a member of the G protein coupled receptors (GPCR) family, classically known to couple Gαq and engage β-arres...