Quantitative Fluorescence Measurement of Cardiac Na+/Ca2+ Exchanger Inhibition by Kinetic Analysis in Stably Transfected HEK293 Cells

Abstract.: We developed a method to quantitatively evaluate the potency of Na+/Ca2+ exchanger (NCX) inhibitors with fluorescence microscopy in NCX1-transfected HEK 293 cells. The reverse mode and forward mode NCX activities were measured as the ascending slope of the early phase increase in cytoplas...

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Main Authors: Namekata Iyuki (Author), Kawanishi Toru (Author), Iida-Tanaka Naoko (Author), Tanaka Hikaru (Author), Shigenobu Koki (Author)
Format: Book
Published: Elsevier, 2006-01-01T00:00:00Z.
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Call Number: A1234.567
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