Genetic contribution of caspase-8 variants and haplotypes to breast cancer risk and prognosis: a case-control study in Iran

• Main Authors: Fahimeh Afzaljavan (Author), Elham Vahednia (Author), Matineh Barati Bagherabad (Author), Fatemeh Vakili (Author), Atefeh Moezzi (Author), Azar Hosseini (Author), Fatemeh Homaei Shandiz (Author), Mohammad Mahdi Kooshyar (Author), Mohammadreza Nassiri (Author), Alireza Pasdar (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Purpose Multiple genome-wide and candidate-gene association studies have been conducted to search for common risk variants of breast cancer. Recent large meta-analyses and consolidating evidence have highlighted the role of the caspase-8 gene in breast cancer pathogenesis. Therefore, this s...