Extracellular cold inducible RNA-binding protein mediates binge alcohol-induced brain hypoactivity and impaired cognition in mice

• Main Authors: Asha Jacob (Author), Yilong Ma (Author), Elham Nasiri (Author), Mahendar Ochani (Author), Joseph Carrion (Author), Shichun Peng (Author), Max Brenner (Author), Patricio T. Huerta (Author), Ping Wang (Author)
• Format: Book
• Published: BMC, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Alcohol abuse affects the brain regions responsible for memory, coordination and emotional processing. Binge alcohol drinking has shown reductions in brain activity, but the molecular targets have not been completely elucidated. We hypothesized that brain cells respond to excessi...