Paeoniflorin Inhibits ASK1-TF Axis by Up-Regulating SOCS3 to Alleviate Radiation Enteritis

• Main Authors: Lei Sheng (Author), Fan Hu (Author), Hanqing Yu (Author), Xueyou Tao (Author), Rumeng Jia (Author), Yufeng Gu (Author), Lu Chen (Author), Hong Kong (Author), Chen Miao (Author), Wenjing Fei (Author), Yang Yang (Author), Jinhui Jia (Author), Xia Zhu (Author), Xueming He (Author), Liang Hu (Author), Jianxin Ma (Author), Wen-Tao Liu (Author), Mi Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiation enteritis is one of the main adverse effects of radiotherapy, presenting with a poorly understood etiology and limited options for therapy. Intestinal inflammation and ischemia are the core mechanisms of radiation enteritis. Suppressor of cytokine signaling 3 (SOCS3) is an endogenous "...