Bruton's Tyrosine Kinase Inhibitor Zanubrutinib Effectively Modulates Cancer Resistance by Inhibiting Anthracycline Metabolism and Efflux

Zanubrutinib (ZAN) is a Bruton's tyrosine kinase inhibitor recently approved for the treatment of some non-Hodgkin lymphomas. In clinical trials, ZAN is often combined with standard anthracycline (ANT) chemotherapy. Although ANTs are generally effective, drug resistance is a crucial obstacle th...

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Main Authors: Lucie Čermáková (Author), Jakub Hofman (Author), Lenka Laštovičková (Author), Lucie Havlíčková (Author), Ivona Špringrová (Author), Eva Novotná (Author), Vladimír Wsól (Author)
Format: Book
Published: MDPI AG, 2022-09-01T00:00:00Z.
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