Effects of repeated alcohol abstinence on within-subject prefrontal cortical gene expression in rhesus macaques

• Main Authors: Robert Hitzemann (Author), Lina Gao (Author), Suzanne S. Fei (Author), Karina Ray (Author), Katinka A. Vigh-Conrad (Author), Tamara J. Phillips (Author), Robert Searles (Author), Rita P. Cervera-Juanes (Author), Rupak Khadka (Author), Timothy L. Carlson (Author), Steven W. Gonzales (Author), Natali Newman (Author), Kathleen A. Grant (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Male rhesus monkeys (n = 24) had a biopsy of prefrontal cortical area 46 prior to chronic ethanol self-administration (n = 17) or caloric control (n = 7). Fourteen months of daily self-administration (water vs. 4% alcohol, 22 h access/day termed "open-access") was followed by two cycles of...