CYP2C19 Genotyping May Provide a Better Treatment Strategy when Administering Escitalopram in Chinese Population

• Main Authors: Xinyi Huang (Author), Chao Li (Author), Chaopeng Li (Author), Zhenyu Li (Author), Xiaohui Li (Author), Jianwei Liao (Author), Tai Rao (Author), Lulu Chen (Author), Lichen Gao (Author), Dongsheng Ouyang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Depression disorder is one of the most serious mental illnesses in the world. Escitalopram is the essential first-line medication for depression disorder. It is the substrate of hepatic cytochrome P450 (CYP) enzyme CYP2C19 with high polymorphism. The effect of CYP2C19 on pharmacokinetics and pharmac...