Bilirubin: an endogenous molecule with antiviral activity in vitro.

• Autori principali: Rosaria eSantangelo (Autore), Cesare eMancuso (Autore), Simona eMarchetti (Autore), Enrico eDi Stasio (Autore), Giovambattista ePani (Autore), Giovanni eFadda (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2012-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Bilirubin-IX-alpha (BR) is the final product of heme metabolism through the heme oxygenase/biliverdin reductase (HO/BVR) system. Previous papers reported on the microbicidal effects of the HO by-products biliverdin-IX-alpha, carbon monoxide and iron, through either direct or indirect mechanisms. In...