Up-Regulation of Intestinal Phosphate Transporter NaPi-IIb (SLC34A2) by the Kinases SPAK and OSR1

• Main Authors: Myriam Fezai (Author), Bernat Elvira (Author), Jamshed Warsi (Author), Mossadok Ben-Attia (Author), Zohreh Hosseinzadeh (Author), Florian Lang (Author)
• Format: Book
• Published: Karger Publishers, 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: SPAK (SPS1-related proline/alanine-rich kinase) and OSR1 (oxidative stress-responsive kinase 1), kinases controlled by WNK (with-no-K[Lys] kinase), are powerful regulators of cellular ion transport and blood pressure. Observations in gene-targeted mice disclosed an impact of SPAK/OS...