Co-Amorphization of Kanamycin with Amino Acids Improves Aerosolization

• Main Authors: Bishal Raj Adhikari (Author), Kārlis Bērziņš (Author), Sara J. Fraser-Miller (Author), Keith C. Gordon (Author), Shyamal C. Das (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Different formulation techniques have been investigated to prepare highly aerosolizable dry powders to deliver a high dose of antibiotics to the lung for treating local infections. In this study, we investigated the influence of the co-amorphization of a model drug, kanamycin, with selected amino ac...