Sodium-bile acid co-transporter is crucial for survival of a carcinogenic liver fluke Clonorchis sinensis in the bile.

• Main Authors: Fuhong Dai (Author), Won Gi Yoo (Author), Yanyan Lu (Author), Jin-Ho Song (Author), Ji-Yun Lee (Author), Youngro Byun (Author), Jhang Ho Pak (Author), Woon-Mok Sohn (Author), Sung-Jong Hong (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The liver fluke Clonorchis sinensis inhabits the bile ducts, where bile concentration disparities across the fluke cell membrane can cause bile intoxication. Sodium-bile acid co-transporter (SBAT) plays a crucial role in bile acid recycling. The process by which SBAT imports bile acids is electrical...