A Multi-Objective Approach for Anti-Osteosarcoma Cancer Agents Discovery through Drug Repurposing

• Main Authors: Alejandro Cabrera-Andrade (Author), Andrés López-Cortés (Author), Gabriela Jaramillo-Koupermann (Author), Humberto González-Díaz (Author), Alejandro Pazos (Author), Cristian R. Munteanu (Author), Yunierkis Pérez-Castillo (Author), Eduardo Tejera (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteosarcoma is the most common type of primary malignant bone tumor. Although nowadays 5-year survival rates can reach up to 60-70%, acute complications and late effects of osteosarcoma therapy are two of the limiting factors in treatments. We developed a multi-objective algorithm for the repurposi...