Development of an in vitro compound screening system that replicate the in vivo spine phenotype of idiopathic ASD model mice

• Main Authors: Kazuma Maeda (Author), Miki Tanimura (Author), Yusaku Masago (Author), Tsukasa Horiyama (Author), Hiroshi Takemoto (Author), Takuya Sasaki (Author), Ryuta Koyama (Author), Yuji Ikegaya (Author), Koichi Ogawa (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Autism Spectrum Disorder (ASD) is a developmental condition characterized by core symptoms including social difficulties, repetitive behaviors, and sensory abnormalities. Aberrant morphology of dendritic spines within the cortex has been documented in genetic disorders associated with ASD and ASD-li...