Nucleoside analog GS‐441524: pharmacokinetics in different species, safety, and potential effectiveness against Covid‐19

• المؤلفون الرئيسيون: Henrik Berg Rasmussen (مؤلف), Ragnar Thomsen (مؤلف), Peter Riis Hansen (مؤلف)
• التنسيق: كتاب
• منشور في: Wiley, 2022-04-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract GS‐441524, the parent nucleoside of remdesivir, has been proposed to be effective against Covid‐19 based on in vitro studies and studies in animals. However, randomized clinical trials of the agent to treat Covid‐19 have not been conducted. Here, we evaluated GS‐441524 for Covid‐19 treatmen...