Design and Synthesis of Novel Thiazolo[5,4-d]pyrimidine Derivatives with High Affinity for Both the Adenosine A<sub>1</sub> and A<sub>2A</sub> Receptors, and Efficacy in Animal Models of Depression
New compounds with a 7-amino-2-arylmethyl-thiazolo[5,4-d]pyrimidine structure were synthesized and evaluated in vitro for their affinity and/or potency at the human (h) A<sub>1</sub>, hA<sub>2A</sub>, hA<sub>2B</sub>, and hA<sub>3</sub> adenosine recep...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2021-07-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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