Pulmonary fibroblast-specific delivery of siRNA exploiting exosomes-based nanoscaffolds for IPF treatment

• Main Authors: Haoyu Lu (Author), Xulu Liu (Author), Mengjun Zhang (Author), Hriday Bera (Author), Wenwen Xu (Author), Huiyang Jiang (Author), Xing Zhao (Author), Lan Wu (Author), Dongmei Cun (Author), Mingshi Yang (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary disease that leads to interstitial inflammation, lung damage, and eventually life-threatening complications. Among various pathologic factors, Smad4 is a pivotal molecule involved in the progression and exacerbation of IPF. It mediates n...