Protective Effect of Adenosine A2B Receptor Agonist, BAY60-6583, Against Transient Focal Brain Ischemia in Rat

• Main Authors: Ilaria Dettori (Author), Lisa Gaviano (Author), Filippo Ugolini (Author), Daniele Lana (Author), Irene Bulli (Author), Giada Magni (Author), Francesca Rossi (Author), Maria Grazia Giovannini (Author), Felicita Pedata (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cerebral ischemia is a multifactorial pathology characterized first by an acute injury, due to excitotoxicity, followed by a secondary brain injury that develops hours to days after ischemia. During ischemia, adenosine acts as an endogenous neuroprotectant. Few studies have investigated the role of...