Ferulic acid attenuates non-alcoholic steatohepatitis by reducing oxidative stress and inflammation through inhibition of the ROCK/NF-κB signaling pathways

• Autori principali: Ziheng Wei (Autore), Yurun Xue (Autore), Yucong Xue (Autore), Jie Cheng (Autore), Guoping Lv (Autore), Li Chu (Autore), Zhihong Ma (Autore), Shengjiang Guan (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2021-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Ferulic acid (FA) is a natural polyphenol compound existing in many plants. The purpose of this study was to investigate the effect of FA on non-alcoholic steatohepatitis (NASH) induced by high-cholesterol and high-fat diet (HCHF) and its possible mechanism. Rats were fed HCHF for 12 weeks to establ...