Shift in SARS-CoV-2 variants of concern from Delta to Omicron was associated with reduced hospitalizations, increased risk of breakthrough infections but lesser disease severity

• Main Authors: Fridah Mwendwa (Author), Akbar Kanji (Author), Ali Raza Bukhari (Author), Unab Khan (Author), Ayesha Sadiqa (Author), Zain Mushtaq (Author), Nosheen Nasir (Author), Syed Faisal Mahmood (Author), Uzma Bashir Aamir (Author), Zahra Hasan (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: COVID-19 epidemiology changed with the emergence of SARS-CoV-2 variants of concern (VOC). Pakistan administered mostly inactivated vaccines. We investigated the association between VOC and breakthrough infections in a mixed-vaccination-status population of Karachi. Methods: We investigat...