Prohibitin 1 interacts with p53 in the regulation of mitochondrial dynamics and chemoresistance in gynecologic cancers

• Main Authors: Bao Kong (Author), Chae Young Han (Author), Se Ik Kim (Author), David A. Patten (Author), Youngjin Han (Author), Euridice Carmona (Author), Dar-Bin Shieh (Author), Annie C. Cheung (Author), Anne-Mar (Author), Mary-Ellen Harper (Author), Yong Sang Song (Author), Benjamin K. Tsang (Author)
• Format: Book
• Published: BMC, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mitochondrial dynamics (e.g. fission/fusion) play an important role in controlling chemoresistance in representative gynecologic malignancies, ovarian and cervical cancer. Processing the long form of Optic atrophy (L-Opa)1 is a distinctive character of mitochondrial fragmentation...