Gap Junctions Are Involved in the Rescue of CFTR-Dependent Chloride Efflux by Amniotic Mesenchymal Stem Cells in Coculture with Cystic Fibrosis CFBE41o- Cells

• Main Authors: Annalucia Carbone (Author), Roberto Zefferino (Author), Elisa Beccia (Author), Valeria Casavola (Author), Stefano Castellani (Author), Sante Di Gioia (Author), Valentina Giannone (Author), Manuela Seia (Author), Antonella Angiolillo (Author), Carla Colombo (Author), Maria Favia (Author), Massimo Conese (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We previously found that human amniotic mesenchymal stem cells (hAMSCs) in coculture with CF immortalised airway epithelial cells (CFBE41o- line, CFBE) on Transwell® filters acquired an epithelial phenotype and led to the expression of a mature and functional CFTR protein. In order to explore the ro...