Effect of enhanced expression of connexin 43 on sunitinib-induced cytotoxicity in mesothelioma cells

• Main Authors: Miaki Uzu (Author), Hiromi Sato (Author), Ryota Yamada (Author), Tatsuro Kashiba (Author), Yukihiro Shibata (Author), Katsunori Yamaura (Author), Koichi Ueno (Author)
• Format: Book
• Published: Elsevier, 2015-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Connexin (Cx) makes up a type of intercellular channel called gap junction (GJ). GJ plays a regulatory role in cellular physiology. The Cx expression level is often decreased in cancer cells compared to that in healthy ones, and the restoration of its expression has been shown to exert antiprolifera...