Immunotherapeutic Efficacy of IgY Antibodies Targeting the Full-Length Spike Protein in an Animal Model of Middle East Respiratory Syndrome Coronavirus Infection

• Auteurs principaux: Sherif A. El-Kafrawy (Auteur), Aymn T. Abbas (Auteur), Sayed S. Sohrab (Auteur), Ashraf A. Tabll (Auteur), Ahmed M. Hassan (Auteur), Naoko Iwata-Yoshikawa (Auteur), Noriyo Nagata (Auteur), Esam I. Azhar (Auteur)
• Format: Livre
• Publié: MDPI AG, 2021-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Identified in 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe and often fatal acute respiratory illness in humans. No approved prophylactic or therapeutic interventions are currently available. In this study, we developed chicken egg yolk antibodies (IgY Abs) specific...