A New Experimental Polytrauma Model in Rats: Molecular Characterization of the Early Inflammatory Response

• Autores principales: Sebastian Weckbach (Autor), Mario Perl (Autor), Tim Heiland (Autor), Sonja Braumüller (Autor), Philip F. Stahel (Autor), Michael A. Flierl (Autor), Anita Ignatius (Autor), Florian Gebhard (Autor), Markus Huber-Lang (Autor)
• Formato: Libro
• Publicado: Hindawi Limited, 2012-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Background. The molecular mechanisms of the immune response after polytrauma are highly complex and far from fully understood. In this paper, we characterize a new standardized polytrauma model in rats based on the early molecular inflammatory and apoptotic response. Methods. Male Wistar rats (250 g...