Anti-Interleukin-22-Neutralizing Antibody Attenuates Angiotensin II-Induced Cardiac Hypertrophy in Mice

• Main Authors: Jing Ye (Author), Ling Liu (Author), Qingwei Ji (Author), Ying Huang (Author), Ying Shi (Author), Lei Shi (Author), Jianfang Liu (Author), Menglong Wang (Author), Yao Xu (Author), Huimin Jiang (Author), Zhen Wang (Author), Yingzhong Lin (Author), Jun Wan (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Interleukin- (IL-) 22 is considered a proinflammatory cytokine. Recent evidence has demonstrated that it plays a role in cardiovascular diseases. In the recent study, we investigate whether IL-22 is involved in cardiac hypertrophy. Methods. Angiotensin II was used to build hypertrophy mo...