The Study of [3H]-Cycloprolylglycine Pharmacokinetics in Rat Blood

• Main Authors: G. I. Kovalev (Author), Yu. A. Zolotarev (Author), A. K. Dadayan (Author), S. I. Shram (Author), A. A. Abdullina (Author), E. V. Vasileva (Author), G. B. Kolyvanov (Author), V. P. Zherdev (Author)
• Format: Book
• Published: LLC "Publisher OKI", 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Resume. The objective of this study is to evaluate pharmacokinetic parameters of tritium-labeled cycloprolylglycine [3H] -CPG following intravenous bolus administration of 5.7 μg (2 mCi). [3H] -CPG was prepared by solid-state catalytic isotopic exchange with spillover-tritium. It was found that plas...