Characterization and In Vitro and In Vivo Evaluation of Tacrolimus-Loaded Poly(ε-Caprolactone) Nanocapsules for the Management of Atopic Dermatitis

• Main Authors: Guilherme dos Anjos Camargo (Author), Leandro Ferreira (Author), Diego José Schebelski (Author), Amanda Martinez Lyra (Author), Fernanda Malaquias Barboza (Author), Bruna Carletto (Author), Adriana Yuriko Koga (Author), Betina Christi Semianko (Author), Daniele Toniolo Dias (Author), Leandro Cavalcante Lipinski (Author), Andressa Novatski (Author), Vijayasankar Raman (Author), Jane Manfron (Author), Jessica Mendes Nadal (Author), Paulo Vitor Farago (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Tacrolimus (TAC) is a drug of natural origin used in conventional topical dosage forms to control atopic dermatitis. However, direct application of the drug often causes adverse side effects in some patients. Hence, drug nanoencapsulation could be used as an improved novel therapy to mit...