Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas

• Main Authors: María Gabriela Morales (Author), Johanna Abrigo (Author), María José Acuña (Author), Robson A. Santos (Author), Michael Bader (Author), Enrique Brandan (Author), Felipe Simon (Author), Hugo Olguin (Author), Daniel Cabrera (Author), Claudio Cabello-Verrugio (Author)
• Format: Book
• Published: The Company of Biologists, 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immobilization is a form of disuse characterized by a loss of strength and muscle mass. Among the main features are decreased IGF-1/Akt signalling and increased ubiquitin-proteasome pathway signalling, which induce greater myosin heavy chain degradation. Activation of the classical renin-angiotensin...