TOX as a potential target for immunotherapy in lymphocytic malignancies

• Hoofdauteurs: Chaofeng Liang (Auteur), Shuxin Huang (Auteur), Yujie Zhao (Auteur), Shaohua Chen (Auteur), Yangqiu Li (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2021-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract TOX (thymocyte selection-associated HMG BOX) is a member of a family of transcriptional factors that contain the highly conserved high mobility group box (HMG-box) region. Increasing studies have shown that TOX is involved in maintaining tumors and promoting T cell exhaustion. In this revie...