TOX as a potential target for immunotherapy in lymphocytic malignancies

• المؤلفون الرئيسيون: Chaofeng Liang (مؤلف), Shuxin Huang (مؤلف), Yujie Zhao (مؤلف), Shaohua Chen (مؤلف), Yangqiu Li (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2021-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract TOX (thymocyte selection-associated HMG BOX) is a member of a family of transcriptional factors that contain the highly conserved high mobility group box (HMG-box) region. Increasing studies have shown that TOX is involved in maintaining tumors and promoting T cell exhaustion. In this revie...