Polysialic acid-functionalized liposomes for efficient honokiol delivery to inhibit breast cancer growth and metastasis

• Main Authors: Xin Li (Author), Shuang Guan (Author), Henan Li (Author), Dong Li (Author), Dan Liu (Author), Jing Wang (Author), Wenquan Zhu (Author), Guihua Xing (Author), Liling Yue (Author), Defu Cai (Author), Qi Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractTo improve the anti-metastasis effects of honokiol (HNK) on breast cancer, we designed cationic liposomes (Lip) in which HNK was encapsulated into Lip, and its surface was modified with negatively charged polysialic acid (PSA-Lip-HNK) for efficient treatment of breast cancer. PSA-Lip-HNK pos...