Polyethyleneimine (PEI) mediated siRNA gene silencing in the Schistosoma mansoni snail host, Biomphalaria glabrata.

Polyethyleneimine (PEI) mediated siRNA gene silencing in the Schistosoma mansoni snail host, Biomphalaria glabrata.

An in vivo, non-invasive technique for gene silencing by RNA interference (RNAi) in the snail, Biomphalaria glabrata, has been developed using cationic polymer polyethyleneimine (PEI) mediated delivery of long double-stranded (ds) and small interfering (si) RNA. Cellular delivery was evaluated and o...

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Main Authors: Matty Knight (Author), Andre Miller (Author), Yijia Liu (Author), Puthupparampil Scaria (Author), Martin Woodle (Author), Wannaporn Ittiprasert (Author)
Format: Book
Published: Public Library of Science (PLoS), 2011-07-01T00:00:00Z.
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