Degradation of Ubiquitin-Editing Enzyme A20 following Autophagy Activation Promotes RNF168 Nuclear Translocation and NF-κB Activation in Lupus Nephritis

• Váldodahkkit: Luxi Zou (Dahkki), Ling Sun (Dahkki), Ruixue Hua (Dahkki), Yu Wu (Dahkki), Linlin Sun (Dahkki), Ting Chen (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Karger Publishers, 2023-03-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The correlation between ubiquitin-editing enzyme A20 and E3 ubiquitin ligase ring finger protein (RNF) 168 has been reported to be critical for repair of DNA damage. This study aimed to evaluate the potential role of this regulatory interaction in the pathogenesis of lupus nephritis (LN). The expres...