The biology of MDR1-P-glycoprotein (MDR1-Pgp) in designing functional antibody drug conjugates (ADCs): the experience of gemtuzumab ozogamicin
BACKGROUND: The treatment of cancer remains a formidable challenge owing to the difficulties in differentiating tumor cells from healthy cells to ameliorate the disease without causing intolerable toxicity to patients. In addition, the emergence of MDR1-Pgp mediated multi-drug resistance (MDR) it is...
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| Formaat: | Boek |
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Istituto Superiore di Sanità€,
2013-06-01T00:00:00Z.
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Internet
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A1234.567 |
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| Kopie 1 | Beschikbaar |