Enhancing the Quality of Rivaroxaban Exposure Estimates Using Prothrombin Time in the Absence of Pharmacokinetic Sampling
Prothrombin time (PT) is a measure of coagulation status and was assessed in the majority of patients in the rivaroxaban phase II and III clinical trials as a pharmacodynamic marker. In the absence of sufficient phase III pharmacokinetic (PK) data to provide individual exposure measures for input in...
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Materyal Türü: | Kitap |
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Wiley,
2019-11-01T00:00:00Z.
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A1234.567 |
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Kopya Bilgisi 1 | Kütüphanede |