Predicting Volume of Distribution in Neonates: Performance of Physiologically Based Pharmacokinetic Modelling

The volume of distribution at steady state (Vss) in neonates is still often estimated through isometric scaling from adult values, disregarding developmental changes beyond body weight. This study aimed to compare the accuracy of two physiologically based pharmacokinetic (PBPK) Vss prediction method...

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Main Authors: Pieter-Jan De Sutter (Author), Phebe Rossignol (Author), Lien Breëns (Author), Elke Gasthuys (Author), An Vermeulen (Author)
Format: Book
Published: MDPI AG, 2023-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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