Preparation and Evaluation of the Cytoprotective Activity of Micelles with DSPE-PEG-C60 as a Carrier Against Doxorubicin-Induced Cytotoxicity

• Główni autorzy: Beihua Xu (Autor), Zhongpeng Ding (Autor), Ying Hu (Autor), Ting Zhang (Autor), Senlin Shi (Autor), Guangmao Yu (Autor), Xuchen Qi (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

To deliver doxorubicin (DOX) with enhanced efficacy and safety in vivo, fullerenol-modified micelles were prepared with the amphiphilic polymer DSPE-PEG-C60 as a carrier, which was synthesized by linking C60(OH)22 with DSPE-PEG-NH2. Studies of its particle size, PDI, zeta potential, and encapsulatio...