Preparation and Evaluation of the Cytoprotective Activity of Micelles with DSPE-PEG-C60 as a Carrier Against Doxorubicin-Induced Cytotoxicity

• Autori principali: Beihua Xu (Autore), Zhongpeng Ding (Autore), Ying Hu (Autore), Ting Zhang (Autore), Senlin Shi (Autore), Guangmao Yu (Autore), Xuchen Qi (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

To deliver doxorubicin (DOX) with enhanced efficacy and safety in vivo, fullerenol-modified micelles were prepared with the amphiphilic polymer DSPE-PEG-C60 as a carrier, which was synthesized by linking C60(OH)22 with DSPE-PEG-NH2. Studies of its particle size, PDI, zeta potential, and encapsulatio...